95 - Quantitative Stereological Morphometric Analysis of the Lateral Angle of the External Auditory Canal by Computed Tomography in Sudanese Population

Poster Board Number: 95
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Co-authors:

Shamail Elmustafa, Najran University Hospital - ER Department - Najran University Hospital; Qurashi Ali, Professor of Anatomy and Radiology - Professor of Anatomy, Anatomy, Rector, National University; Bünyamin Şahin, Professor of Anatomy - Professor of Anatomy, Anatomy, Tokat Gaziosmanpaşa, Faculty of Medicine, Department of Anatomy; Mert Nahir, Assistant Professor of Anatomy - Assistant Professor of Anatomy, Anatomy, Tokat Gaziosmanpaşa University, Faculty of Medicine; Amani Elfaki - Professor of Anatomy, Anatomy, Alzaeim Alazhari University, Faculty of Medicine

Abstract Body :
Introduction:Anthropometry used to understand human anatomy variations, correlation, and the experimental studies to analyze the applied anatomy, morphometry aspects of the external auditory canal (EAC) in human beings since there are great inter-individual variability and structural variations that may occur regarding the other adjacent structures. Otitis media (OM) describes a spectrum of pathologies involve in middle ear infection. OM is considered a potentially severe disease due to the risk of complications, which remains significant when compared to ‎the rates seen in developed countries.‎ObjectivesTo determine and compare the quantitative morphometrical and morphological analysis of the lateral angle of the EAC in healthy volunteers with patients with OM, using highly resolution computed tomography (HRCT)MethodsThis study approved by University of Gezira, Faculty of Medicine IRB, all Volunteers was singed the informed consent. HRCT images was collected from Khartoum State, Sudan, from 140 volunteers (patient 70 and healthy 70), the ‎percentage of cases as 52.9 % (n=74) of the patients were females and 47.1% (n=66) are males. The range of the groups was (18-40 years). The CT images performed for the both genders to measure the EAC lateral angle. To measurement the EC, we used ImageJ software (V 1.52a); OsiriX image processing application for Mac (OsiriX Lite) to display images for the external ear area of the skull’s temporal bone. The level of significance was set at P-value < 0.05. Chi-Square test was used, ROC, PSS V.22, and s SAS (V.9).ResultsThe total number n=140 (240 auditory canals), (as patients=70 and healthy=70), the ‎percentage of cases as 52.9 % (n=74) of the females and 47.1% (n=66) are males. The number of cases in each side was 140 (70 right, 70 left). The range of groups was (18-40 years).‎The mean of the lateral angle (LA) is ±142.68, If the LA value was ≤ 135.67 was classified as OM patient. The quantitative ‎variables distribution (QVD) of LA showed that the mean was ‎‎142.68 ‎‎ (± 12.87). QVD by a case ‎in LA showed that in patients with OM, the average was 142.68 ‎‎(± 12.87); ‎while in the healthy ‎was 143 (±12.06), ‎t ±0.286, and the P-value ‎‎< 0.775. QVD of LA by gender showed that the ‎male's mean ‎143.08 (±13.19), and the female's mean 142.33 (±12.66). The ‎ROC analysis showed that the LA variable was not a significant predictor for patients with OM ‎‎(p=0.509).Conclusions:Using the HRCT images for EAC measurement and beneficial in OM diagnosis. SignificanceMorphometric evaluation of the external auditory canal (EAC) help to know anatomical basis, knowledge of normal values and the anatomy of the EAC is essential in determination of temporal and ear diseases.RecommendationsAnatomy and morphometry of the ‎auditory canal help in diagnosis of the EAC pathology.